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The Department of Health and Social Care (DHSC) has warned that the shortage of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) will continue, with supply not expected to return to normal until at least the end of 2024

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Currently in the UK, injectable GLP-1 receptor agonists such as semaglutide (Ozempic) and dulaglutide (Trulicity) are well-established treatments recommended by NICE (NG28) for specific indications in type 2 diabetes management, with some formulations also approved for weight management

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Notably, cell migration is a key element in HF development